We are overturning a stone in natural product drug discovery—capturing biology that has been missed, as it exists in nature.

Our goal is to access and unlock the value of a remarkable chemical space that conventional discovery has largely overlooked.

Natural chemistry is shaped by evolution, ecology, and biological competition. While conventional natural product discovery has focused on a relatively narrow range of cultured microorganisms, we pursue chemistry wherever biology creates it—across underrepresented organisms, complex ecological interactions, and wild environments where unique metabolites emerge in response to natural selection.

Our proprietary fungal collection, sourced from the forests of Kapoose Creek, British Columbia is one example of this philosophy, providing access to biology and natural chemistry rarely represented in conventional discovery libraries. We explored fungi from fruiting bodies, animals, insects & plants, where community interactions drive the production of unique bioactive chemistry with increased relevance to human physiology. The collection is rich in exotic species, with ~2/3 of strains having no match in any public database.

Our exploration strategy integrates newly acquired natural chemistry with existing resources, continuously expanding the foundation for therapeutic discovery. From remote field expeditions to strategic partnerships with industry, academia and communities, we are systematically broadening the chemical diversity available to the unEarth Rx Platform, providing an ever-growing source of biologically relevant starting points for new medicines.